AcroPak™ 200 capsules with Supor™ EKV membrane, a Pall Life Sciences product, provides additional debris holding, which makes them well suited for use with high turbidity, high bioburden solutions.
Newer technology recommended for simplified scale-up
High filtration area and compact size are ideal for upscale trials
Minimal hold-up volume
Good wettability for reliable integrity test
Sealed membrane and housing uses fusion technology to eliminate potential extractables
Gamma sterilized, non-pyrogenic, and provided with a removable filling bell (except sanitary flange option)
Hydrophilic polyethersulfone membrane for low adsorption and wide chemical compatibility
Very high flow rates and consistently higher total solution throughputs due to superior porosity over other membranes
Materials of Construction
Filter Media: Supor™EKV [hydrophilic polyethersulfone (PES)] membrane
Housing, Vent Plug, and Support Material: Polypropylene
Filling Bell: Polycarbonate (no filling bell on sanitary option)
Sealing Technology: Thermal bonding without adhesives
Pore Size
0.2 μm
Effective Filtration Area
220 cm2
Dimensions
Housing Length: 12094: 10.5 cm (4.1 in.); 12095: 7.3 cm (2.9 in.)
Housing Diameter: 5.3 cm (2.1 in.) without vent, 6.7 cm (2.6 in.) with vent
Inlet/Outlet Connections
12094: 6.4 - 12.7 mm (1/4 - 1/2 in.) stepped hose barb inlet and outlet
12095: 13 mm (1/2 in.) sanitary flange inlet/outlet
Typical Hold-Up Volume (with 10 psi air purge)
< 6 mL
Maximum Operating Temperature
60°C (140°F) at 2.1 bar (210 kPa, 30 psi)
Maximum Operating Pressure
4.1 bar (410 kPa, 60 psi) at ambient temperature
Recommended Integrity Test Minimum Bubble Point - Water
> 3.32 bar (332 kPa, 48 psi)
Typical Liquid Flow Rate
350 mL/min/0.1 bar (241 mL/min/psi)
Bacterial Retention
Lot samples retain a minimum of 107 cfu/cm2 of B. diminuta per modified ASTM F838, current revision
Endotoxin Level
< 0.25 EU/mL using Limulus Amoebocyte Lysate (LAL) test
Biological Safety
Passes United States Pharmacopeia (USP) Biological Reactivity Test, In Vivo <88>
Sterilization
Capsules that have been sterilized by gamma radiation can be autoclaved for 1 x 1/2hr cycle at 125°C.
Applications
Designed to quickly process difficultto- filter solutions within 5-21 L, such as serum, serum-supplemented culture media, and ascites fluid
Ideal in situations where rapid filtration or short processing times are essential
For buffers, tissue culture media, and other biological fluids. Newer technology recommended for simplified scale-up. High filtration area and compact size are ideal for upscale trials.
