AcroPak™ 20 filters with Supor™ EKV membrane, a Pall Life Sciences product, feature built-in MachV asymmetric prefilter layer for maximum flow and throughput performance.
Newer technology recommended for simplified scale-up
Disposable design reduces labor costs associated with assembling, cleaning, and testing stainless steel filter holders
Encapsulated format for ease of use
Extended life with built-in MachV asymmetric prefilter layer for maximum flow and throughput performance
Low adsorption and high chemical compatibility with hydrophilic polyethersulfone membrane for high compatibility over the entire pH range and low protein binding
Gamma-irradiated, non-pyrogenic, and non-cytotoxic
Inherently hydrophilic for reliable integrity testing
Materials of Construction
Filter Media: Supor EKV [hydrophilic polyethersulfone (PES)] membrane
Housing, Vent Plug, and Support Material: Polypropylene
Filling Bell: Polycarbonate (no filling bell on sanitary flange option)
Sealing Technology: Thermal bonding without adhesives
Effective Filtration Area
20 cm2
Housing, Vent Plug, and Support Material: Polypropylene
Filling Bell: Polycarbonate
Sealing Technology: Thermal bonding without adhesives
Pore Size
0.2 μm
Effective Filtration Area
20 cm2
Dimensions
Housing Length: 8.3 cm (3.3 in.)
Housing Diameter: 6.7 cm (2.7 in.)
Inlet/Outlet Connections
Stepped hose barbs 6.4 - 12.7 mm (1/4 - 1/2 in.) diameter with female slip luer ID in the hose barb
Typical Hold-Up Volume (with 10 psi air purge)
< 2.5 mL
Maximum Operating Temperature
60°C (140°F) at 1.0 bar (100 kPa, 15 psi)
Dimensions
Housing Length: 8.3 cm (3.3 in.)
Housing Diameter: 6.7 cm (2.7 in.)
Inlet/Outlet Connections
Stepped hose barbs 6.4 - 12.7 mm (1/4 - 1/2 in.) diameter with female slip luer ID in the hose barb
Typical Hold-Up Volume (with 10 psi air purge)
< 2.5 mL
Maximum Operating Temperature
60°C (140°F) at 1.0 bar (100 kPa, 15 psi)
Maximum Operating Pressure
4.1 bar (410 kPa, 60 psi) at 21 - 24°C (70 - 75°F)
Recommended Integrity Test Minimum Bubble Point - Water
3.32 bar (332 kPa, 48 psi)
Bacterial Retention
Lot samples retain a minimum of 107 cfu/cm2 of B. diminuta per modified ASTM F838, current revision
Endotoxin Level
< 0.25 EU/mL using Limulus Amoebocyte Lysate (LAL) test
Biological Safety
Passes United States Pharmacopeia (USP) Biological Reactivity Test, In Vivo <88>
Sterilization
Can withstand one autoclave cycle at 125°C (257°F) for 60 minutes; water wet capsule prior to autoclaving
PN 12247 is sterilized by gamma irradiation and individually packaged
Applications
Ideal for filtering aqueous solutions, cell culture media, and serum
Small- to medium-volume sterile filtration, typically up to 2 L
Suitable for use with fluids containing dilute proteins, preservatives, or other critical components
Sterile filtration of media and buffers
