AcroPak™ 400, 800, 1500, and Acro™ 500 capsules with Supor™ EKV membrane, a Pall Life Sciences product, are designed for cost-effective filtration of buffers, tissue culture media, and other biological solutions
Newer technology recommended for simplified scale-up
Disposable design reduces labor costs associated with assembling, cleaning, and testing stainless steel filter holders
Encapsulated format for ease of use
Extended life with built-in MachV asymmetric prefilter layer for maximum flow and throughput performance
Low adsorption and high chemical compatibility with hydrophilic polyethersulfone membrane for high compatibility over the entire pH range and low protein binding
Gamma-irradiated, non-pyrogenic, and non-cytotoxic
Inherently hydrophilic for reliable integrity testing.
Materials of Construction
AcroPak 400, 800, 1500:
Filter Media: Supor EKV [hydrophilic polyethersulfone (PES)] membrane
Housing, Vent Plug, and Support Material: Polypropylene
Filling Bell: Polycarbonate (no filling bell on sanitary flange option)
Sealing Technology: Thermal bonding without adhesives
Acro 500:
Filter Media: Supor EKV membrane
(hydrophilic polyethersulfone)
Housing: Polycarbonate
Filter Support: Polyester
Core & Vent Plug: Polypropylene
Sealing Technology: Polyurethane
Pore Size
AcroPak 400, 800, 1500:
0.2 μm
Acro 500:
0.65/0.2 µm
Effective Filtration Area
400 Series: 375 cm2
800 Series: 750 cm2
1500 Series: 1500 cm2
Acro 500: 500 cm2
Dimensions
Housing Diameter (including valves): 9.4 cm (3.7 in.)
Acro 500 Diameter: 6.0 cm (2.4 in.)
400 Series Housing Length:
12460: 11.7 cm (4.6 in.)
12461: 15.7 cm (6.2 in.)
800 Series Housing Length:
12463: 15.7 cm (6.2 in.)
12464: 19.7 cm (7.7 in.)
1500 Series Housing Length:
12466: 17.4 cm (6.8 in.)
12467: 21.0 cm (8.3 in.)
Acro 500 Series Housing Length:
13.3 cm (5.2 in.)
Inlet/Outlet Connections
400 Series
12460: 25 - 38 mm (1 - 1.5 in.) sanitary flange inlet/outlet connection
12461: 13 mm (1/2 in.) hose barb inlet/outlet connection
800 Series
12463: 25 - 38 mm (1 - 1.5 in.) sanitary flange inlet/outlet connection
12464: 13 mm (1/2 in.) hose barb inlet/outlet connection
1500 Series
12466: 25 - 38 mm (1 - 1.5 in.) sanitary flange inlet/outlet connection
12467: 13 mm (1/2 in.) hose barb inlet/outlet connection
Acro 500 Series
12337: Hose Barb fittings accept 12.7 mm (1/2 in.) ID tubing
Maximum Operating Temperature
AcroPak 400, 800, and 1500:
40°C (104°F) at 4.0 bar (400 kPa, 58 psi)
Acro 500:
60 °C (140 °F) at 2.1 bar (210 kPa, 30 psi)
Maximum Operating Pressure
AcroPak 400, 800, and 1500:
5.2 bar (520 kPa, 75 psi) at 20°C (68°F)
Acro 500:
3.4 bar (340 kPa, 50 psi) at ambient temperature
Recommended Integrity Test Minimum Bubble Point - Water
AcroPak 400, 800, and 1500:
3.32 bar (332 kPa, 48 psi) Typical Water Flow Rate
Acro 500:
1.2 bar (120 kPa, 17 psi)
Typical Water Flow Rate
400 Series: 700 mL/min/0.1 bar (483 mL/min/psi)
800 Series: 1.5 L/min/0.1 bar (1.0 L/min/psi)
1500 Series: 3.2 L/min/0.1 bar (2.2 L/min/psi)
Bacterial Retention
400, 800, and 1500 Series:
Lot samples retain a minimum of 107 cfu/cm2 of B. diminuta per modified ASTM F838, current revision
Acro 500 Series:
Lot samples retain a minimum 107 cfu/cm2 of B. diminuta per modified ASTM F838, current revision.
Endotoxin Level
< 0.25 EU/mL using Limulus Amoebocyte Lysate (LAL) test
Biological Safety
Passes United States Pharmacopeia (USP) Biological Reactivity Test, In Vivo <88>
Sterilization
400, 800, and 1500 Series:
Sterilized by gamma irradiation and individually packaged
Acro 500:
Sterilized by gamma irradiation and individually packed. Do NOT autoclave
Applications
Suitable for sterile filtration of a wide range of fluids, including:
Buffers
Biological fluids
Cell culture media
Ophthalmic products
