AcroPak™ 500, 1000, & 1500 capsules with Supor™ membrane, a Pall Life Sciences product, deliver fast, final filtration and high throughputs for liquid volumes up to 150 L
Provides higher throughputs and faster flow rates than similarly-sized competitive devices
Ideal for solutions requiring low protein binding
Saves money by increasing throughput with available built-in prefilter
100% integrity testing assures sterile filtrate
0.1 μm Supor membrane version reduces mycoplasma levels in cell culture media
Fusion-welded components eliminate the potential for release of extractables from sealing adhesives
Sterilization by gamma irradiation eliminates potential contamination by EtO residuals.
Materials of Construction
Filter Media: Supor [hydrophilic polyethersulfone (PES)] membrane
Housing, Vent Plug, and Filter Support: Polypropylene
Sealing Technology: Thermal bonding
Filling Bell: Polycarbonate
Pore Size
0.1/0.1, 0.2/0.2, 0.8/0.2, and 0.8/0.45 μm
Effective Filtration Area
500 Series: 500 cm2
1000 Series: 1000 cm2
1500 Series: 1500 cm2
Dimensions
Housing Diameter: 6.9 cm (2.7 in.)
Overall Length (Without Filling Bell):
500 Series: 14.5 cm (5.7 in.)
1000 Series: 19.3 cm (7.6 in.)
1500 Series: 22.9 cm (9.0 in.)
Inlet/Outlet Connections
500 and 1000 Series: 6.4 - 12.7 mm (1/4 - 1/2 in.) stepped hose barb with filling bell on outlet
1500 Series: 12.7 mm (1/2 in.) straight hose barb, no filling bell on outlet
Typical Hold-Up Volume (with 10 psi air purge)
500 Series: 30 mL
1000 Series: 45 mL
Maximum Operating Temperature
60°C (140°F) at 2.1 bar (210 kPa, 30 psi)
Maximum Operating Pressure
Continuous: 4.1 bar (410 kPa, 60 psi) at ambient temperature
Recommended Integrity Test Minimum Bubble Point – Water
0.2 μm: 3.5 bar (350 kPa, 51 psi)
0.45 μm: 1.7 bar (170 kPa, 24 psi)
60% IPA/40% h3O (v:v)
0.1 μm: 2.4 bar (240 kPa, 35 psi)
Bacterial Retention
0.1/0.1 μm Capsules: Lot samples retain a minimum of 107 cfu/cm2 of A. laidlawii challenge per modified ASTM F838, current revision
0.2 μm Capsules: Lot samples retain a minimum of 107 cfu/cm2 of B. diminuta per modified ASTM F838, current revision
Endotoxin Level
< 0.25 EU/mL using Limulus Amoebocyte Lysate (LAL) test
Biological Safety
Passes United States Pharmacopeia (USP) Biological Reactivity Test, In Vivo <88>
Sterilization
Sterilized by gamma irradiation
If desired, autoclave once only prior to use at 121 - 123°C (250 - 253°F) for a maximum of 20 min.
Applications
Large-volume media preparation
Pilot-scale manufacturing
Liquids requiring prefiltration, such as serum-containing media
Sterile filtration of buffers
Point-of-use filtration for laboratory water
Reduce mycoplasma with the 0.1 µm pore size
