AcroCap™ positive pressure devices, a Pall Life Sciences product, are for sterilization or clarification of up to three liters of serum-free cell and tissue culture media, media additives, and other aqueous solutions.
Integral hydrophobic vent prevents air lock.
Sterilization by gamma irradiation eliminates the risk of cytotoxic residuals from EtO sterilization.
Reduce mycoplasma. Choose 0.1 μm pore size Supor™membrane.
Compatible with most positive-pressure systems. Inlet accepts 6.4 mm (1/4 in.) tubing or any male slip luer.
Materials of construction
Filter Media: Supor™ [hydrophilic polyethersulfone (PES)] membrane
Housing: Modified acrylic
Vent: 0.02 μm PTFE
Filling Bell: Modified acrylic
Effective Filtration Area
15 cm2
Inlet/Outlet Connections
6.4 mm (1/4 in.) hose barb, inner taper accepts male slip luer; removable filling bell attached to outlet
Typical Hold-Up Volume (with air purge)
< 2 mL
Maximum Operating Temperature
55°C (131°F)
Maximum Operating Pressure
2.1 bar (210 kPa, 30 psi)
Typical Water Flow Rate
mL/min at 1.0 bar (100 kPa, 15 psi)
0.1 μm: 90
0.2 μm: 220
0.45 μm: 500
Endotoxin Level
< 0.25 EU/mL using Limulus Amoebocyte Lysate (LAL) test
Biological Safety
Passes United States Pharmacopeia (USP) Biological Reactivity Test, In Vivo <88>
Sterilization
Sterilized by gamma irradiation and individually packaged
Applications
Well suited for sterilization of solutions that tend to foam when filtered under vacuum
Fast, positive-pressure filtration of aqueous solutions up to 3 L. Sterilization by gamma irradiation eliminates the risk of cytotoxic residuals from ethylene oxide sterilization. Integral hydrophobic vent prevents air lock.
