System do filtracji tangencjalnej LV Centramate

Filtracja tangencjalna prowadzona dla układów do 4 L.
LV Centramate Lab tangential flow filtration System, a Pall Life Sciences product, is a scale-up/scale-down device for development of tangential flow filtration (TFF) processes and biopharmaceutical small batch production.

Identical path lengths provide linear scale-up to Pall Centramate and Centrasette™ cassette holders. The LV Centramate holder may be attached to other laboratory TFF systems to improve their scalability characteristics.

Low hold-up volume allows high concentration factors to be achieved from small starting volumes. A complete TFF system scalable to full production plant can be optimized using the volumes typically generated in the development or discovery lab.

Easy connections through luer lock fitted ports with polished 316L stainless steel to ensure the same compatibility characteristics as production-scale Centrasette™ holders.

All product-wetted parts comply with pharmaceutical standards.
Materials of Construction
Membrane Cassette Filter Media: Supor™[hydrophilic polyethersulfone (PES)], and Omega™ (low protein-binding, modified PES) membranes

Cassette Hardware
Cassette Holder Top and Bottom Plates: Type 316L stainless steel
Tie Rods and Washers: Type 304 stainless steel
Nuts: Bronze

Length: 22.8 cm (9 in.) Width: 8.3 cm (3.3 in.)

Typical Starting Volume
0.02 m2 (0.2 ft2) cassette: 60 - 4,000 mL

Typical Hold-Up Volume
< 1 mL

Maximum Operating Temperature
121°C (250°F)

Maximum Operating Pressure
5 bar (500 kPa, 75 psi)

Typical Cross Flow Rate Per 0.02 m2 (0.2 ft2) Cassette (L/min)
Suspended Screen 0.2 - 0.4
Screen 0.12 - 0.16

Screen Selection Guideline
Suspended screen for light-tomoderate particle load solutions
Screen for optimized processing of particle-free protein solutions to high concentrations

Concentration of biomolecules
Recovery and purification of biomolecules from cell culture supernatants and lysates
Diafiltration, desalting, and buffer exchange of biomolecules
Fractionation of mixed molecule solutions
Product Product Name
OS005C11P2 5K, 0.02 m² (0.2 ft²), suspended screen (1/pkg)
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